Mokuho'oniki Islet Seabird Sanctuary is a 10-acre islet off the coast of East Moloka'i. This islet is also nearby another seabird sanctuary is Kanaha Rock Islet Seabird Sanctuary. Mokuho'oniki Islet is one of six seabird sanctuary islets managed by the Division of Forestry and Wildlife. Mokuho'oniki also goes by the nickname "Elephant Island" due to its' resemblance to an elephant from an aerial view. Due to its' status as a seabird sanctuary, this islet is closed to the public.

Mokuho'oniki Islet is home to roughly 31 plant species, nine of which are endemic. This islet also protects four different seabird species such as: Koa'e 'Ula (Red-tailed Tropic Bird), 'Ou (Bulwer's Petrel), 'Ua'u (Hawaiian Dark-Rumped Petrel), 'Ua'u Kani (Wedge-Tailed Shearwater).